Promethazine HCl and Codeine Phosphate Oral Alternative ought to be utilised with caution in individuals with impairment of hepatic perform, and sufferers needs to be monitored intently for respiratory melancholy, sedation, and hypotension.
e., a number of copies of the gene for cytochrome P450 isoenzyme 2D6 or large morphine concentrations). Kids with rest apnea could possibly be specially sensitive for the respiratory depressant effects of codeine.
Hold a summary of all the merchandise you utilize (which include prescription/nonprescription drugs and herbal merchandise) and share it using your health practitioner and pharmacist. Tend not to start, cease, or change the dosage of any medicines without the need of your physician's acceptance.
Tell your medical doctor If the cough won't recover in 5 days. Also, notify your physician Should your condition will get even worse, or For those who have a headache that doesn't disappear, fever, or rash. These may very well be symptoms of a serious professional medical challenge and should be checked by a doctor.
Promethazine really should not be utilized by young children more youthful than 2 many years because it could result in critical (perhaps fatal) slow/shallow respiration. This problem has happened In spite of normal doses During this age group.
Pregnancy Exams: Diagnostic pregnancy tests determined by immunological reactions in between HCG and anti-HCG may possibly lead to Fake-unfavorable or Untrue-beneficial interpretations.
This medication may interfere with certain lab checks (including urine pregnancy assessments, pores and skin allergy exams), probably creating Bogus examination final results. Be certain lab staff and all of your Medical doctors know you use this drug.
Promethazine is perfectly absorbed from the gastrointestinal tract. Scientific effects are apparent inside of 20 minutes soon after oral administration and usually past four to six hours, While they may persist so long as twelve hrs.
Promethazine may lower seizure threshold. It ought to be utilized with warning in persons with seizure Problems or in people that are making use of concomitant prescription drugs, which include narcotics or neighborhood anesthetics, which may also have an impact on seizure threshold.
Postmarketing situations of respiratory melancholy, which include fatalities have been described with usage of promethazine in pediatric patients.
Choose this medication by mouth with or with out meals as directed by your medical doctor, usually just about every 4 to 6 several hours as desired. This medication is often taken with food items if tummy upset takes place. Consume a lot of fluids if you use this medication Unless of course usually directed by your health care provider.
This medication could cause you to a lot more sensitive towards the sun. Restrict your time inside the Sunlight. Keep away from tanning booths and sunlamps. Use sunscreen and wear protective outfits when outdoors. Convey to your medical doctor instantly if you obtain sunburned or have pores and skin blisters/redness.
When employed for an extended time, this medication may well not get the job done as well and will involve different dosing. Speak with your medical professional if this medication stops Doing the job effectively.
Coupled with its needed consequences, a medication could trigger some unwanted outcomes. Although not most of these Unintended effects may well manifest, when they do occur Promethazine codeine syrup they may need medical attention.